Characterization Scientist

The incumbent will participate in the formulation and process development of biotherapeutics. This position will be responsible for performing analytical testing and characterization of candidate molecules by using various biophysical, biochemical and particulates characterization techniques as well as supporting laboratory operations and maintenance. This is a laboratory-based position performing formulation and process development activities specifically for biotherapeutic products from pre-clinical and Ph I clinical trials through late stage, license application and commercialization. Furthermore, this position will assist in data compilation, data presentations, report authoring, and department documentation support. Positions are full-time, working Monday-Friday 8am-5pm, overtime as needed. Candidates currently living within commutable distance to Andover, MA are encouraged to apply.

Responsibilities

Support the development of parenteral formulations for biotherapeutic modalities such as monoclonal antibodies, antibody drug conjugates, proteins, mRNA and vaccines; Perform rapid, comprehensive characterization of candidate molecules to determine the stability profile using biophysical, biochemical and particulates characterization techniques such as HPLC (SE-HPLC, IEX, HIC, RP-HPLC), Capillary Gel electrophoresis (CGE), imaged Capillary Electrophoresis (iCE), Spectroscopy techniques, light obscuration, microflow imaging and additional characterization techniques; Provide general laboratory support, including ordering/replacement of reagents and consumables, general maintenance of equipment, continuous improvement activities, and participating in periodic lab inspections; Interact effectively with a multidisciplinary team of scientists for formulation optimization and overall candidate progression; Prepare data summary presentations, provide data verification support, compile data, and use lab-based systems such as Empower and electronic laboratory notebooks; Communicate effectively with laboratory scientists, project managers and colleagues from numerous functions

Requirements

At least a BS in Pharmaceutics, Chemistry, Chemical/Biochemical Engineering, Pharmacy, Biochemistry, Bioengineering, Biotechnology, Biology or equivalent; 1+ years of industry experience utilizing some sort of chromatography (preferably HPLC); Familiarity with biologics such as proteins, enzymes, monoclonal antibodies, vaccines, mRNA, or antibody drug conjugates and how to characterize them with analytical techniques; Must be eligible to work in the United States indefinitely without restriction or sponsorship (OPT, H1B, etc.)

Nice to have

Familiarity with HPLC, Capillary electrophoresis, and other analytical techniques; Strong computer skills and experience with lab-based computer systems; Ability to collect and analyze data sets

Benefits

Comprehensive medical coverage; Dental and vision options; Life and disability insurance; 401(k) with company match; Paid vacation and holidays