Engineer I, Process Development, Pilot Scale Operations

The Pilot Scale Operations team is seeking a highly skilled and motivated full-time Individual to support Nucleic Acid pilot-scale production. Qualified candidates will have relevant academic or industry experience in solution preparation, RNA processing, sterile fill/finish and/or tangential flow filtration experience, and an understanding of scaling and technology transfer of these unit operations. A successful candidate should have exposure to large and small-scale equipment maintenance and troubleshooting; as well as authoring and updating equipment specific SOPs. This position will require excellent communication and organizational skills, as well as a focus on operational excellence and process optimization. A successful candidate must demonstrate the independent drive and collaborative spirit to operate in a dynamic, fast-paced environment.

Responsibilities

Be the receiving unit for technology transfer from Moderna’s Process Development teams, focusing on nucleic acid development, enzyme reactions, and scale-up; Assist other development scientists / engineers in defining process development and scale-up strategy, and implementing process control strategies; Operate, maintain, and troubleshoot custom equipment used to manufacture Formulations batches; Characterize product attributes through collaboration with analytical and technical teams; Demonstrate and implement lab best practices; Update and write standard operating procedure (SOPs) associated with production as needed; Practice safe work habits and adhere to Moderna safety procedures and guidelines; Adhere to documented waste handling procedures to respect environmental regulations

Requirements

Relevant academic or industry experience in solution preparation, RNA processing, sterile fill/finish and/or tangential flow filtration experience; understanding of scaling and technology transfer of these unit operations; exposure to large and small-scale equipment maintenance and troubleshooting; authoring and updating equipment specific SOPs; excellent communication and organizational skills; focus on operational excellence and process optimization; independent drive and collaborative spirit to operate in a dynamic, fast-paced environment; demonstrated success in bioprocess development, technical problem solving, and technology transfer; BS/BA (required) or MS in Chemistry, Systems, Biomedical or Chemical Engineering, or closely related field with 0-2 years related experience; ability to multi-task in relentless pursuit of successful outcomes; exceptional written and oral communication

Nice to have

Hands-on experience with fermentation, enzymatic reaction, chromatography and/or tangential flow filtration experience

Benefits

Competitive healthcare; voluntary benefit programs; holistic approach to well-being with access to fitness, mindfulness, and mental health support; family planning benefits including fertility, adoption, and surrogacy support; generous paid time off including vacation, volunteer days, sabbatical, global recharge days, and discretionary year-end shutdown; savings and investments to help you plan for the future; location-specific perks and extras; annual discretionary bonus; other incentive compensation; equity award