Lead UX Designer

A Rare Opportunity to Shape the Future of Genomics. Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We're seeking an exceptional Lead UX Designer to own the end-to-end experience strategy and execution for our prenatal diagnostic platform, Unity. This role sits at the intersection of cutting-edge genomics and human-centered design - leading the translation of complex molecular diagnostics into seamless, trustworthy experiences that empower clinicians, patients, and operational teams. As a key member of our product team, you'll lead design from strategic insights through final production, applying systems thinking to design across an interconnected healthcare ecosystem that spans lab processes, electronic health records, provider networks, and patient touchpoints. This is a hybrid position (2-3 days per week at our Menlo Park facilities.)

Responsibilities

Own the complete UX vision and strategy for Unity's patient and provider platforms, from research insights through final implementation; Partner with product leadership to shape roadmaps, define priorities, and determine phased approaches; Apply systems thinking to visualize and simplify complex relationships between patients, providers, lab processes, payer requirements, and data systems; Transform scientific complexity into intuitive digital experiences that build trust and understanding; Translate product strategy into actionable design initiatives; Lead the complete design process from discovery and research through wireframing, prototyping, user testing, and final production-ready deliverables; Create and maintain high-quality design artifacts: user flows, journey maps, wireframes, prototypes, and design system components; Own in-product microcopy and content strategy; Drive the evolution of Unity's design system; Ensure accessibility, regulatory compliance, and ethical considerations are integrated into every design decision; Lead user research initiatives; Advocate for evidence-based design grounded in rigorous user research and testing methodologies; Synthesize insights from clinicians, patients, and operational teams; Champion the user perspective in cross-functional discussions; Oversee and mentor junior designers and UX contractors; Build a culture of design excellence, systems thinking, and user advocacy; Partner with engineers to ensure the experiential quality of what ships matches design intent; Present and defend design decisions to stakeholders; Collaborate with product managers, engineers, clinicians, and genetic counseling teams; Identify opportunities and drive initiatives independently

Requirements

7–10 years of professional experience in UX, product design, or service design; 3+ years in leadership roles with demonstrated ability to own design strategy and guide team members; Proven track record designing in healthcare, biotech, or similarly complex regulated environments; An exceptional portfolio demonstrating systems-level thinking, strategic leadership, and user-centered problem solving from research through final execution; Track record of partnering with product management on prioritization and phased delivery approaches; Expert-level skills in design and prototyping tools: Figma, Sketch, Miro, or similar platforms; Deep understanding of user research methodologies, from generative research to usability testing; Mastery of information architecture, interaction design principles, and UX best practices; Strong grasp of accessibility standards (WCAG) and healthcare regulatory requirements (HIPAA, FDA); Experience creating and maintaining design systems at scale

Nice to have

Experience in both B2B and B2C healthcare product contexts preferred; Background working with AI-powered product experiences a plus

Benefits

Working alongside brilliant, kind, passionate and dedicated colleagues in an empowering environment; Open, transparent culture that includes weekly Town Hall meetings; The ability to indirectly or directly change the lives of hundreds of thousands of patients; Multiple medical benefit options with employee premiums paid 100% on select plans and dependents covered up to 80%; Extremely generous Family Bonding Leave for eligible employees (16 weeks, paid at 100%); Supplemental fertility benefits coverage; Retirement savings program including a 4% Company match; Increased paid time off with increased tenure; Latest and greatest hardware; Free daily on-site lunches provided from top eateries; A variety of perks on campus (state of the art gym, restaurant); Free on-site EV charging; Generous equity options offering; Corporate bonus program