Research Associate - Mass Spectrometry LCMS

Dr. Reddy’s Laboratories Ltd. is a leading multinational pharmaceutical company based across global locations. Each of our 24,000 plus employees comes to work every day for one collective purpose: to accelerate access to affordable and innovative medicines because Good Health Can’t Wait.
We started in 1984 with a modest investment, 20 employees and a bold vision. Today, we have research and development centres, manufacturing facilities or a commercial presence in 66 countries.
For nearly four decades, we have stood for access, affordability and innovation based on the bedrock of deep science, progressive people practices and robust corporate governance. As the pharmaceutical industry evolves and undergoes disruption, we see an opportunity – to strengthen our core further (the next steps) and to build the future (the new bets).
‘The Next and the New’ is how we aim to continue to be the partner of choice – purpose-driven, future-ready and sustainable. Our aim is to reach over 1.5 Bn+ patients across the world by 2030 by growing our core businesses and building for the future with sustainability at the core of our purpose and strategy. Sustainability for us means operating in a manner that respects people, planet and purpose – helping us conserve precious resources, serve our patients, create value for stakeholders, give back to society, fulfil our potential and maintain our integrity and transparency
Dr Reddy’s maintains a work environment, free from discrimination and is an equal opportunity employer. We are committed to employ & nurture all qualified diverse workforce without regard to race, colour religion, nationality, sex, age, disability status, genetics, sexual orientation, gender expression, citizenship or any other characteristic or classification protected by applicable law(s) of the country we operate in. We treasure every talent, and recognize merit and diversity in our organization.
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Responsibilities

Job Summary; Roles & Responsibilities; Deep understanding on protein/mAbs characterization using LC-MS/MS (QTOF, MALDI TOF, 2D LC QTOF, IM QTOF etc.).; Complete, in-dept knowledge on Biosimilars characterization (Intact mass analysis, subunit mass, peptide mapping, PTM analysis, etc.) using LC-MS/MS.; Experience on mAbs bio similarity, CAA using LCMS.; Experience on method development and qualification for various mAb’s using LC-MS/MS.; Knowledge on ADC’s characterization; Knowledge on HCP and MAM workflows is preferred.; Preferred knowledge on Targeted proteomics/Protein quantitation, Impurities analysis and spent media analysis using TQLCMS; Characterization of SSR/Signal peptides; Understanding on good laboratory practices and Good Documentation Practices.; The candidate should have good knowledge and skills to independently plan and execute method development and validation activities for the functional characterization.; To take up new technology initiatives within the development group and to draft primary documents.; Interpret data, draw conclusions, and present data results at group meetings and other forums.; Prepare protocol / report / manuscript as needed, including contributions to writing and reviewing content.; Collaborate with cross-functional teams to support development projects.; Ensuring compliance with Good Documentation Practices (GDP).; Ensure safe practices in the facilities and participate in the organization-based safety and quality initiatives.

Requirements

Educational Qualification; A Master’s degree (M.Sc. or M.Tech. or or M.Pharm.) or Ph.D. in Proteomics, Biotechnology, Biochemistry.; Minimum Work Experience; Master degree with minimum 2-5 years or PhD with 0-1 years of working experience on Method development, qualification, Handling of analytical instruments like HRMS, TQ LCMS, Synapt, Xevo QTOF, 2D LC QTOF etc. Skills & Attributes Technical Skills; An understanding of the analytical Development for Biotherapeutics/ Biosimilars.; In-depth knowledge LCMS QTOF.; Deep understanding of analytical techniques, statistical analysis, data management and analysis. Behavioral Skills; Possesses team-building capability, fostering positive collaboration and cohesion.; Good verbal and written communication skills, facilitating effective interaction.; A strong learning ability, quickly acquiring new knowledge and skills.; Is self-motivated, taking initiative and showing enthusiasm for tasks and responsibilities.; Exhibits troubleshooting skills, effectively identifying and resolving issues.; Good interpersonal skills, fostering positive relationships and effective communication.