Senior Executive Assistant & Office Operations

The Senior Executive Assistant & Office Operations is a highly trusted, senior-level partner responsible for providing exceptional executive support to senior leaders and members of the Research & Development organization while also partnering on key office operations for the Boston location. This role supports a globally distributed leadership team and partners closely with the Senior Executive Assistant to the Chief Medical Officer (CMO) and the Research & Development Leadership Team (RDLT). In addition to executive support, this role serves as the primary owner of office operations and facilities management for the Boston location, partnering with the Director, Corporate & Administrative Services on workplace planning, construction, branding initiatives, and employee experience. Work arrangement: hybrid, with a minimum of two (2) days on-site per week, currently designated as Tuesday and Wednesday. About Beeline Medicines: a clinical-stage biotechnology company focused on developing precision therapies for people living with autoimmune and inflammatory diseases.

Responsibilities

Provide dedicated support to the assigned executives and work closely with assigned functional departments; Provide proactive, high-level executive support, managing complex calendars, travel, expenses, and rapidly evolving priorities; Partner with the Senior Executive Assistant to the CMO and the RDLT to coordinate leadership meetings, strategic planning sessions, governance forums, and other high-priority engagements; Exercise sound judgment in prioritizing meeting requests and managing competing executive demands; Manage complex calendaring across multiple global time zones and facilitate coordination among internal and external stakeholders; Plan and coordinate domestic and international travel, including multi-stop itineraries, executive briefings, and contingency planning; Support executive interactions with key external stakeholders, advisors, investigators, and partners; Serve as a trusted partner who anticipates needs, identifies potential conflicts, and proactively recommends solutions; Coordinate office and pantry supplies, maintaining inventory levels and employee amenities; Review office and facilities-related expenses and identify opportunities for operational efficiencies and cost optimization; Partner on facilities matters, including maintenance requests, vendor relationships, building management coordination, and work orders; Serve as an engaged member of the Executive Assistant team, supporting company-wide initiatives; Support logistics and planning for town halls, leadership meetings, all-hands meetings, company events, employee engagement activities, company-wide mailings, and cross-functional initiatives; Demonstrate flexibility and willingness to support evolving business needs; Perform other duties and responsibilities as assigned

Requirements

Bachelor's degree or equivalent professional experience; Minimum of 15 years of experience supporting C-suite executives and senior leadership teams in fast-paced, global environments; Proven ability to support multiple senior leaders simultaneously with discretion, professionalism, and confidence; Extensive experience working across global time zones and supporting internationally based executives; Experience supporting industry congresses, scientific meetings, and senior level external engagements; Advanced proficiency in Microsoft Office suite, including Outlook, Word, Excel, and PowerPoint; Experience with DocuSign, SharePoint, Coupa, SAP, and Concur or comparable expense management platforms; Strong command of video conferencing and collaboration tools; Comfortable adopting new technologies; Operates with a high degree of autonomy and ownership; Anticipates organizational needs before they surface; Self-directed and confident, with the ability to orient quickly in ambiguous or fast-moving environments; Communicates with clarity, precision, and discretion across all levels of the organization; Navigates sensitive information with professionalism and strict confidentiality; Highly effective interpersonally

Nice to have

Prior experience in biotechnology or life sciences strongly preferred; R&D or clinical development experience is a plus; Familiarity with AI-enabled productivity tools such as Microsoft Copilot is a plus

Benefits

Competitive health and wellness coverage (structure and premiums vary by country); Paid time off, public holidays, and additional leave entitlements in accordance with local requirements; Flexible work arrangements / hybrid schedule; Discretionary annual bonus and long-term incentive award (e.g., equity) may be available