Senior Scientist I - Cell Culture

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube.

We are seeking a highly motivated Senior Scientist I to join our Manufacturing Science and Technology (MSAT) group in the Product Development Science and Technology (PDS&T) organization supporting biologics manufacturing at the AbbVie Bioresearch Center based in Worcester, MA. As part of the PDS&T Biologics organization, our group leads the process technology transfer, continuous improvement, validation, and continuous process verification activities for late-stage and commercial manufacturing of therapeutic proteins for AbbVie. We also provide technical support for manufacturing, GMP compliance, and regulatory filing. The candidate should have extensive experience and comprehensive knowledge in process development, characterization, and validation of cell culture strategies to solve complex challenges across the AbbVie pipeline. The candidate will be expected to mentor and potentially supervise junior level scientists and productively manage several projects simultaneously in a dynamic and rapidly evolving project landscape.

Responsibilities

Lead team on the design, execution, and data-analysis for process development, characterization, optimization, validation, and continuous process verification activities for large-scale GMP cell culture processes.; Identify, evaluate, and develop innovative technologies within the field of cell culture to improve product quality and process efficiency and robustness for biologics manufacturing processes; Lead team on technology and process transfer activities to GMP scale across AbbVie’s GMP manufacturing network.; Solve technical issues and support GMP manufacturing of therapeutic proteins, including organization of deviation investigations.; Participate in cross-functional teams to support CMC sections of regulatory filings; Author technical reports and validation documents; Interact with cross-functional groups (e.g. , process development, protein analytics, manufacturing, quality, and regulatory); Author peer-reviewed articles and patents and present original work in conferences; Expertise in data analysis or programming techniques is preferred with experience in analyzing large complex data sets, including model development.; Highly autonomous and productive in performing laboratory research, requiring only minimal direction from or interaction with supervisor.

Requirements

Bachelor’s Degree or equivalent education and typically 10 years of experience, Master’s Degree or equivalent education and typically 8 years of experience, PhD and no experience necessary.; Possess thorough theoretical and practical understanding of own scientific discipline.

Nice to have

Outstanding record of accomplishment in areas of bioprocess development and/or process validation.; Experience in managing technical professionals; Strong written and oral communication skills and the ability to contribute in a multi-disciplinary environment are essential.; Interacts well with diverse groups within function and maintains strong working relationships with external collaborators.; Demonstrates problem-solving skills and capability to overcome complex issues.; Demonstrate success in coordinating and executing important projects to achieve business unit goals.; Must have a “results-oriented” work ethic and a positive, “can-do” attitude with a strong sense of urgency and self-motivated desire to achieve.