Sr Product Manager

We are seeking a highly motivated and strategic Product Manager to support the commercial launch and ongoing growth of Signatera in Japan. This role will work closely with the U.S.-based Global Product Management organization and the local Japanese commercial team in Japan to execute launch activities, support field readiness, and drive successful adoption of Signatera in Japan.

Responsibilities

Support the execution of commercial launch activities for Signatera in Japan, including pre-launch planning, launch readiness, and post-launch support; Drive adoption and utilization across markets by partnering closely with Sales and Marketing teams; Assist in identifying and addressing local market needs, operational gaps, and customer experience opportunities; Support implementation and optimization of workflows from ordering through results delivery to enhance customer experience; Partner with marketing, medical affairs, and Global Product Management teams to support development and localization of sales training content and support field onboarding materials; Develop clear, scalable materials and documentation to communicate workflows effectively to internal teams, particularly Sales; Support creation and maintenance of sales enablement resources, including pitch decks, FAQs, objection-handling guides, and training documentation; Monitor the competitive landscape, emerging technologies, and clinical trends in MRD and oncology diagnostics in Japan; Synthesize insights into clear recommendations to inform future product strategy and roadmap planning; Contribute to strategic discussions regarding product positioning, differentiation, and market opportunities in Japan; Support development of future product concepts and Target Product Profiles (TPPs) based on market needs and strategic priorities; Lead product management support for clinical trials in Japan; Perform other duties as assigned

Requirements

Fluent in Japanese (native) and English (business level); Bachelor’s degree required; Minimum of 5+ years of experience including product management, commercialization, or product/solution marketing; Experience with next generation sequencing; Demonstrated experience supporting or leading commercial product launches; Ability to travel 25-35% of the time, including some international travel; Flexibility to coordinate some routine overlapping work time with US colleagues; Strong ability to translate strategy into execution and drive cross-functional alignment; Experience with clinical laboratory testing; Advanced proficiency in developing presentations; Ability to understand complex technologies and communicate clear, differentiated value propositions; Strong project and process management skills; Excellent written and verbal communication skills; Experience developing sales enablement materials and leading training initiatives for commercial teams; High attention to detail and strong organizational skills; Proven ability to influence without authority in a matrixed organization

Nice to have

Life sciences or related field preferred; Advanced degree (MS, PhD) preferred; Experience with cell-free DNA preferred; Experience in oncology, diagnostics, or clinical laboratory services strongly preferred; Experience working with products delivered as services is a plus; Recent diagnostics or oncology product management/commercialization experience; Experience in tumor NGS, MRD assay or oncology diagnostics environments preferred; Comfortable collaborating with both local commercial teams and global headquarters stakeholders; Passionate about improving patient outcomes and supporting successful product adoption in a complex environment; Critical thinker and attention to detail; Strong presentation skills

Benefits

Comprehensive medical, dental, vision, life and disability plans; Free testing for employees and immediate family; Fertility care benefits; Pregnancy and baby bonding leave; 401k benefits; Commuter benefits; Employee referral program