HTP Analytical QC Associate Scientist

We are seeking a detail-oriented and proactive Associate Scientist to join our High-Throughput Protein Analytical QC Laboratory. This role is responsible for performing analytical characterization and quality control testing of recombinant proteins generated from high-throughput production workflows. The successful candidate will play a critical role in ensuring protein identity, purity, and overall quality through robust analytical methodologies. This position operates in a data-driven and quality-focused environment where accuracy, reproducibility, and data integrity are essential. The ideal candidate will have hands-on experience with protein analytical techniques and familiarity with laboratory data management systems such as ELN, LIMS, or equivalent platforms.

Responsibilities

Perform routine and non-routine analytical and QC testing to evaluate protein identity, purity, and quality attributes; Execute a range of protein characterization assays, including HPLC/UPLC (e.g., SEC, RP, IEX), Capillary Electrophoresis (CE, iCE/cIEF), SDS-PAGE, Western blot, LC-MS, and endotoxin assays; Prepare samples, reagents, buffers, and standards in accordance with established protocols and assay requirements; Perform sample preparation workflows, including use of automated liquid handling systems where applicable; Analyze, interpret, and document experimental data in ELN, LIMS, or equivalent systems, ensuring compliance with data integrity standards (e.g., ALCOA+ principles); Support method troubleshooting and optimization, ensuring assay robustness, reproducibility, and consistency across runs; Maintain laboratory instruments and ensure proper calibration and performance, supporting compliance with quality and safety standards; Collaborate with cross-functional teams (e.g., protein production, process development) to support project timelines and deliverables; Contribute to continuous improvement initiatives, including method refinement, workflow efficiency, and data quality enhancement

Requirements

BS or MS in Biochemistry, Analytical Chemistry, Biotechnology, or a related field with 2+ years of relevant experience in protein analytical characterization or QC; Hands-on experience with protein analytical techniques such as HPLC/UPLC, CE, SDS-PAGE, Western blot, LC-MS, or endotoxin assays; Familiarity with protein characterization workflows, including purity, aggregation, and identity analysis; Experience with laboratory data systems (ELN, LIMS, or similar) and strong documentation practices; Strong attention to detail and commitment to data integrity, accuracy, and reproducibility

Nice to have

Experience in a CRO/CDMO or regulated QC environment is preferred

Benefits

Medical, dental, and vision insurance; 401(k) retirement plan with a company match that vests fully on day one; Paid parental leave after three months of employment; Paid time off including vacation time, personal time, sick time, floating holidays, and company holidays; Flexible spending and health savings accounts; Life and AD&D insurance; Short- and long-term disability coverage; Legal assistance; Supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance; Commuter benefits; Well-being initiatives; Peer-to-peer recognition programs