Senior Research Associate or Associate Scientist, Translational Medicine

Reporting to the Senior Scientist, Translational Medicine we are seeking an experienced, motivated, detail-oriented, and highly skilled Senior Research Associate/Associate Scientist within our Translational Medicine team. Under scientific and technical supervision, the individual will be primarily responsible for developing and performing autoantibody evaluation assays (MSD, Luminex, ELISA) assays and other molecular based assays such as dPCR. As part of the Translational Medicine team, the individual must be able to perform qualified assays on clinical trial participant materials, adhering to internal compliance standards.

Responsibilities

With guidance from a Senior Scientist, Translational Medicine, perform assays on clinical samples and potentially pre-clinical samples; Perform qualified or validated molecular-based assays (Luminex, dPCR, MSD, ELISA, etc.) on clinical samples to inform on cell product persistence and efficacy in humans; Participate in generating, qualifying, and validating GLP-like assays and contribute to the development of corresponding SOPs; Interface heavily with the electronic lab notebook (eLN) system and sample management system; accurately capture data in a timely manner, ensuring data integrity and protocol compliance using an eLN; Maintain GDP-compliant and detailed records for clinical sample lifecycle, including receipt, usage, inventory, and related documentation; Assist with clinical sample accessioning while maintaining close attention to metadata entry and accuracy; Gain opportunities to learn and perform cell-based assays, such as flow cytometry and cell killing assays; Manage multiple internal projects and workstreams simultaneously; Perform laboratory-associated tasks in accordance with GLP and Cabaletta Bio laboratory safety policies and SOPs; Support general maintenance of laboratory space and contribute to weekly laboratory activities

Requirements

MS degree in Biology, Immunology, Engineering, or a related field, or a Bachelor’s degree with 2+ years of experience in an academic laboratory or the biotechnology industry is required; Experience with molecular-based assays such as ELISA, MSD, Luminex, and/or dPCR platforms; Significant laboratory experience, including aseptic technique, mammalian cell culture, and DNA extraction; Ability to follow SOPs and adhere to good documentation practices; Highly organized and efficient, with the ability to work independently. Strong problem-solving skills preferred; Ability to communicate clearly and effectively, both verbally and in writing; Desire to be part of a growing organization that uses cutting-edge science; Strong team orientation and passion for continuous self-development; Comfortable working in a fast-paced small company environment and able to adjust workload based on changing priorities

Nice to have

Experience in protocol design, qualification, and SOP generation; Experience with qPCR/dPCR platforms; Experience with autoantibody evaluation assays; Experience with clinical sample handling and inventory management is strongly preferred; Experience troubleshooting, qualifying, or validating molecular-based assays; Experience in the biotechnology industry or in a startup industrial setting; Previous experience with GLP/GCP and ICH regulations; Prior experience using an electronic laboratory notebook system; involvement in system development is a plus

Benefits

health and retirement; PTO; stock option plans