Sr. Research Associate, RNA Innovation

Moderna is seeking a Senior Research Associate for a position in the RNA Innovation team, located in Cambridge, MA. In this early research laboratory-based position, the candidate will focus on the chemical biology of mRNA, discovering and characterizing how RNA modifications impact RNA metabolism and performance. The researcher will design and plan experiments implementing in vitro biochemical approaches as well as cell line techniques to investigate mRNAs of interest. In addition to strong technical skills, the role requires a high level of initiative, ownership, and the ability to drive projects forward with urgency. Prior academic or industrial experience in a laboratory focusing on RNA is strongly preferred. Ideal candidates should have a strong interest in the biochemistry of nucleic acids, enjoy working in a dynamic environment, and be flexible in working both individually and within cross-functional teams.

Responsibilities

Focus on the chemical biology of mRNA, discovering and characterizing how RNA modifications impact RNA metabolism and performance; Design and plan experiments implementing in vitro biochemical approaches as well as cell line techniques to investigate mRNAs of interest; Develop and execute methods to study the stability and translation of modified mRNA using cell lines and in vitro biochemistry; Implement analytical approaches such as RT/qPCR, chromatography, and mass spectrometry to analyze RNAs; Develop and execute Next Generation Sequencing library preparation protocols; Maintain cell lines, equipment, scientific records, and an organized lab space; Communicate scientific findings to colleagues and collaborators in formal and informal settings

Requirements

MS in Biochemistry, Chemical Biology, Chemistry, Molecular Biology, Chemical Engineering, or closely related field with 2+ years of experience; Candidates with 3-5 years of experience are preferred; Knowledge of biochemistry/chemical biology of nucleic acids; Experience working with RNA; This position is site-based, requiring you to be at Moderna’s site full-time; This position is not eligible for remote work; Candidates must already hold work authorization in US and be able to maintain that status without the need for future sponsorship

Nice to have

Prior academic or industrial experience in a laboratory focusing on RNA is strongly preferred; Strong interest in the biochemistry of nucleic acids; Enjoy working in a dynamic environment; Flexible in working both individually and within cross-functional teams; Experience with mammalian cell culture and relevant techniques preferred; Experience with some analytical approaches relevant to RNA (such as but not limited to gel electrophoresis, qPCR, Next Generation Sequencing, chromatography, etc.); Excellent interpersonal, organizational, and collaborative skills, attention to detail, and the ability to work independently and effectively in a highly dynamic environment; Ability to quickly master new scientific techniques and concepts; Excellent record-keeping; A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative

Benefits

Competitive healthcare, plus voluntary benefit programs; A holistic approach to well-being, with access to fitness, mindfulness, and mental health support; Family planning benefits, including fertility, adoption, and surrogacy support; Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown; Savings and investments to help you plan for the future; Location-specific perks and extras; Annual discretionary bonus, other incentive compensation, or equity award