Senior Manager, Clinical Procurement

Deciphera, a member of Ono Pharmaceutical Co., Ltd., is a biopharmaceutical company focused on discovering, developing, and commercializing important new medicines and providing hope to people living with cancer, neurologic and autoimmune disease. Deciphera is leveraging its proprietary switch-control kinase inhibitor platform and deep expertise in kinase biology to develop a broad portfolio of innovative medicines. In addition to advancing multiple product candidates from Deciphera’s platform in clinical studies, QINLOCK® (ripretinib) is Deciphera’s switch-control kinase inhibitor approved in many countries including the European Union and the United States for the treatment of adult patients with advanced gastrointestinal stromal tumor (GIST) who have received prior treatment with 3 or more kinase inhibitors, including imatinib. ROMVIMZA® (vimseltinib) is a kinase inhibitor approved in the United States for adult patients with symptomatic tenosynovial giant cell tumor (TGCT) for which surgical resection will potentially cause worsening functional limitation or severe morbidity, and in the European Union for adult patients with TGCT associated with clinically relevant physical function deterioration and in whom surgical options have been exhausted or would induce unacceptable morbidity or disability.

The spirit of collaboration that has brought medications to life continues to guide how we operate, grow, and discover new breakthroughs. We cultivate an inclusive culture that values curiosity, creativity, and shared accountability—empowering individuals to challenge the unknown together.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

The Senior Manager, Clinical Procurement is responsible for driving sourcing and procurement activities supporting global clinical trials and development programs. This role partners closely with Clinical Operations, Clinical Development, Legal, and Finance to develop and execute sourcing strategies, negotiate complex contracts, and ensure timely delivery of high-quality services from external suppliers. The individual will drive value through cost optimization, supplier performance management, and risk mitigation while ensuring compliance with applicable regulations and internal policies. This role requires strategic thinking, strong stakeholder engagement, and deep knowledge of clinical trial procurement.

Responsibilities

Develop and execute sourcing strategies for clinical trial services (e.g., CROs, central labs, biometrics, imaging, eCOA, specialty vendors); Lead end-to-end strategic sourcing events including RFI/RFP/RFQ processes; Drive competitive bidding, cost benchmarking, and total cost of ownership analysis; Establish and maintain category strategies aligned with clinical development plans; Ownership and maintenance of assigned clinical subcategories/studies; Lead negotiation of Master Service Agreements (MSAs), Statements of Work (SOWs), and change orders (COs); Partner with Legal to ensure contract terms align with company risk tolerance and compliance requirements; Partner with stakeholders to ensure contracts are fit for purpose to support the appropriate clinical categories; Ensure timely execution of contracts to support clinical trial timelines within agreed cycle times; Identify and mitigate contractual and commercial risks; Serve as a trusted business partner to Clinical Operations and cross-functional teams; Provide procurement guidance to study teams across the clinical asset lifecycle; Support study startup timelines through proactive planning and supplier alignment; Communicate sourcing strategies, timelines, and risks to key stakeholders; Drive continuous improvement initiatives and supplier innovation; Ensure adherence to procurement policies, procedures, and systems (e.g., P2P processes); Contribute to cross functional support of vendor governance; Support audit and inspection readiness and maintain compliance with GxP requirements

Requirements

Bachelor’s degree in Business, Life Sciences, or related field; 8+ years of procurement/sourcing experience, including 4+ years supporting clinical trials in biotech/pharma; Demonstrated experience negotiating complex clinical service agreements (e.g., CROs, central labs); Strong understanding of clinical development processes and vendor landscape; Proven ability to lead cross-functional initiatives and manage multiple priorities; Excellent negotiation, communication, and stakeholder management skills; Experience with procurement systems (e.g., Oracle Fusion, Ariba, or similar ERP/eSourcing tools)

Nice to have

Advanced degree (MBA, MS, or equivalent); Experience supporting global, multi-phase clinical trials; Knowledge of GxP, regulatory requirements, and clinical compliance standards; Experience with category management and strategic sourcing methodologies; Exposure to supplier risk management and third-party due diligence processes; Strong analytical skills, including cost modeling and financial evaluation; Prior experience in a fast-paced, growth-oriented biotech environment

Benefits

Competitive salary and annual bonus.; Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more.; Generous parental leave and family planning benefits.; Outstanding culture and opportunities for personal and professional growth.