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Origination Associate

Flagship Pioneering, Inc. Cambridge, United States
Full-time On-site work

Publication date: 06/11/2026

Flagship Pioneering is seeking a highly motivated and innovative Origination Associate to join its interdisciplinary team at the confluence of biology and technology. The role involves co-leading new company origination from the very early stage, from ideation and hypothesis development through to building the early scientific team and shaping company culture. The position is full-time and on-site in Cambridge, MA.

Responsibilities

Identify and investigate emerging frontiers in biology and technology that could unlock entirely new markets and industries; Generate bold venture hypotheses, run rapid experiments (conceptual, computational, or prototype-driven), and rigorously pressure-test assumptions; Help translate early-stage concepts into venture designs, including technical thesis, experimental planning, product architecture, and potential go-to-market approaches; Contribute directly to the conception and launch of high-potential ventures, with a hands-on role in their earliest stages; Work closely with scientists, product thinkers, and entrepreneurs to fuse technical insights with market potential; Translate complex information into clear, actionable insights for Flagship's venture creation process; Stay ahead of emerging scientific advances, bringing creativity and critical thinking to areas others overlook; Ideate, research, and refine novel venture hypotheses and develop the scientific roadmap and business case; Co-lead new company origination from the very early stage, including identifying and recruiting scientific partners and advisors, establishing foundational intellectual property, and building and leading the early scientific team; Collaborate with stakeholders across the Flagship ecosystem to accelerate company formation and growth

Requirements

Advanced degree (PhD or equivalent experience) in a scientific field, particularly biology, bioengineering, chemistry, or related disciplines; 2+ years of experience post-PhD in research, technology, startups, or other environments that demand both analytical rigor and creative problem-solving; Proven ability to rapidly become conversant in new areas of science and engage thought leaders at the deepest level of technological understanding; Strong scientific curiosity and creativity; Strong communication skills, including the ability to craft compelling written narratives and presentations; Excellent analytical skills and ability to synthesize and communicate complex information rapidly and effectively; Proven ability to thrive in ambiguous, fast-moving, entrepreneurial contexts; able to prioritize, pivot, and push forward without a playbook; Unmatched sense of urgency with willingness to go the extra mile to drive success; Passion for growth and development, with openness to giving and receiving feedback and a track record of acting on feedback; Genuine passion for innovation, venture creation, and exploring uncharted technological spaces
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